Human Primary Diabetic Vein Endothelial Cells
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Product Data Sheet
Technical Documentation
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Product Overview
Description
Human Primary Diabetic Vein Endothelial Cells (often abbreviated as HPDVEC) are a specialized primary cell type used extensively in diabetes research, vascular biology, and complications related to hyperglycemia.
Guarantee expansion for a minimum of 2-5 population doubles.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPD017
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Positive for endothelial markers: Positive for endothelial cell
markers, e.g., CD31 (PECAM-1), VE-Cadherin, von Willebrand
Factor (vWF) (inferred from standard endothelial cell
characterization).
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Atherosclerosis Research: Studying how high gluc…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Atherosclerosis Research: Studying how high glucose accelerates plaque formation. -Wound Healing: Investigating why diabetic patients have poor blood flow and delayed wound closure (angiogenesis assays like tube formation). -Microvascular Complications: Modeling retinopathy (eye)
Suitable for -atherosclerosis research: studying how high glucose accelerates plaque formation. -wound healing: investigating why diabetic patients have poor blood flow and delayed wound closure (angiogenesis assays like tube formation). -microvascular complications: modeling retinopathy (eye) studies and research applications
nephropathy (kidney)
Suitable for nephropathy (kidney) studies and research applications
and neuropathy (nerve damage). -Pharmacology: Testing new drugs designed to protect the endothelium
Suitable for and neuropathy (nerve damage). -pharmacology: testing new drugs designed to protect the endothelium studies and research applications
reduce oxidative stress
Suitable for reduce oxidative stress studies and research applications
or improve insulin sensitivity at the vascular level. -Permeability Studies: Measuring how diabetes causes blood vessels to become "leaky."
Suitable for or improve insulin sensitivity at the vascular level. -permeability studies: measuring how diabetes causes blood vessels to become "leaky." studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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