Human Primary Diabetic Gallbladder Smooth Muscle Cells
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Product Overview
Description
Characterization Markers
Characterized by positive expression of smooth muscle cell-specific. alpha-actin .
Key Features
Catalog Number: NBPDS004
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
Diabetic Gastroenteropathy: Studying how chronic …
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Diabetic Gastroenteropathy: Studying how chronic hyperglycemia leads to motility disorders in the biliary tract. Pharmacodynamics (PD): Testing new drugs (prokinetic agents) designed to restore contraction in the diabetic gallbladder. Mechanotransduction: Studying how the physical stiffness of the diabetic environment affects cell signaling (YAP/TAZ pathways). Inflammation (Lipotoxicity): Investigating how high glucose combined with high lipids (common in Type 2 Diabetes) causes cellular damage. Advanced Glycation End-products (AGEs): Studying the receptors for AGEs (RAGE) on smooth muscle cells and their role in inflammation.
Suitable for diabetic gastroenteropathy: studying how chronic hyperglycemia leads to motility disorders in the biliary tract. pharmacodynamics (pd): testing new drugs (prokinetic agents) designed to restore contraction in the diabetic gallbladder. mechanotransduction: studying how the physical stiffness of the diabetic environment affects cell signaling (yap/taz pathways). inflammation (lipotoxicity): investigating how high glucose combined with high lipids (common in type 2 diabetes) causes cellular damage. advanced glycation end-products (ages): studying the receptors for ages (rage) on smooth muscle cells and their role in inflammation. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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