Human Dermal Microvascular Endothelial Cells
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Product Overview
Description
Human Dermal Microvascular Endothelial Cells (HDMECs) are a type of primary endothelial cell found in the skin’s microvasculature. They are defined as endothelial cells in direct contact with blood, forming the lining of blood vessels and playing essential roles in wound healing and tissue repair by facilitating the delivery of oxygen and nutrients while removing waste products.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0005
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELL MARKERS & CHARACTERIZATION
HDMECs are identified and quality-controlled using several specific markers:
* von Willebrand Factor (vWF) / Factor VIII endothelial identity marker.
* CD31 (PECAM-1) platelet-endothelial cell adhesion molecule.
* Podoplanin used to distinguish lymphatic from blood vascular endothelial cells.
* DiI-Ac-LDL uptake functional assay for endothelial identity.
Quick Facts
Product Type
Human Endothelial cells
Viability
>98% viable (Trypan Blue exclusion)
Applications
-Vascular regeneration and tissue engineering: Us…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Vascular regeneration and tissue engineering: Used to promote neovascularization in engineered tissues and grafts. -Cell-based therapies: Potential for treating ischemic diseases (e.g.
Suitable for -vascular regeneration and tissue engineering: used to promote neovascularization in engineered tissues and grafts. -cell-based therapies: potential for treating ischemic diseases (e.g. studies and research applications
myocardial infarction
Suitable for myocardial infarction studies and research applications
peripheral artery disease). -Disease modeling: Useful for studying vascular diseases
Suitable for peripheral artery disease). -disease modeling: useful for studying vascular diseases studies and research applications
angiogenesis
Suitable for angiogenesis studies and research applications
and endothelial dysfunction. -Drug screening and toxicity testing: Serve as a platform for evaluating vascular responses to new compound. -Research on endothelial biology and development: Help elucidate mechanisms of blood vessel formation and repair.
Suitable for and endothelial dysfunction. -drug screening and toxicity testing: serve as a platform for evaluating vascular responses to new compound. -research on endothelial biology and development: help elucidate mechanisms of blood vessel formation and repair. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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