hTert Immortalized Human Retinal Microvascular Pericytes
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Product Overview
Description
hTert Immortalized Human Retinal Microvascular Pericytes are a stable, telomerase-immortalized cell line derived from primary human retinal microvascular pericytes. Immortalization is achieved through ectopic expression of human telomerase reverse transcriptase (hTERT), which arrests telomere shortening and promotes sustained mitosis, conferring an extended in vitro lifespan while preserving the genetic stability and functional characteristics of the primary parent cells.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP0025-IChTert
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Quick Facts
Product Type
Immortalized Endothelial
Viability
>95% viable (Trypan Blue exclusion)
Applications
* Pathophysiological studies of retinal vascular …
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
* Pathophysiological studies of retinal vascular diseases
Suitable for * pathophysiological studies of retinal vascular diseases studies and research applications
including diabetic retinopathy * Investigation of pericyte endothelial cell interactions and blood-retinal barrier function * Modeling of angiogenesis
Suitable for including diabetic retinopathy * investigation of pericyte endothelial cell interactions and blood-retinal barrier function * modeling of angiogenesis studies and research applications
pericyte dropout
Suitable for pericyte dropout studies and research applications
and basement membrane changes * Drug discovery and assessment of novel therapeutic agents targeting retinal microvasculature * Co-culture models to study the neurovascular unit and endothelial-pericyte signaling under normoxic
Suitable for and basement membrane changes * drug discovery and assessment of novel therapeutic agents targeting retinal microvasculature * co-culture models to study the neurovascular unit and endothelial-pericyte signaling under normoxic studies and research applications
hypoxic
Suitable for hypoxic studies and research applications
or hyperglycemic conditions
Suitable for or hyperglycemic conditions studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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