hTert immortalized GFP-Human Brain Microglia Cells
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Product Overview
Description
Human Brain Microglia Cells are isolated from healthy human brain tissue, and GFP-Immortalized Human Brain Microglia Cells are infected with lentiviruses expressing hTERT and GFP with puromycin. The hTERT (human Telomerase Reverse Transcriptase) gene is used as an immortalization agent to extend the replicative lifespan of the cells.
hTERT Immortalized GFP-Human Brain Microglia Cells combine the authentic biology of primary human microglia with the practical advantages of a stable, fluorescently trackable cell line making them a powerful tool for CNS disease modeling, neuroinflammation research, and drug screening assays.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP0040-IChTertGFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Quick Facts
Product Type
Immortalized Endothelial
Viability
>95% viable (Trypan Blue exclusion)
Applications
Microglia cells are known to be activated by infl…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Microglia cells are known to be activated by inflammatory factors/cytokines/chemokines in neurodegenerative diseases including Alzheimer's disease
Suitable for microglia cells are known to be activated by inflammatory factors/cytokines/chemokines in neurodegenerative diseases including alzheimer's disease studies and research applications
Parkinson's disease
Suitable for parkinson's disease studies and research applications
Huntington's disease
Suitable for huntington's disease studies and research applications
ALS
Suitable for als studies and research applications
and stroke. Human immortalized microglial cells can be further genetically manipulated to express and produce additional proteins
Suitable for and stroke. human immortalized microglial cells can be further genetically manipulated to express and produce additional proteins studies and research applications
peptides
Suitable for peptides studies and research applications
or prodrugs
Suitable for or prodrugs studies and research applications
including a diverse range of chemokines
Suitable for including a diverse range of chemokines studies and research applications
cytokines
Suitable for cytokines studies and research applications
and various marker proteins
Suitable for and various marker proteins studies and research applications
growth factors
Suitable for growth factors studies and research applications
neurotrophic molecules
Suitable for neurotrophic molecules studies and research applications
and anti-apoptotic molecules. Immortalized Human Microglia Cell Lines also allow the establishment of in vitro models for High Throughput and High Content Screening.
Suitable for and anti-apoptotic molecules. immortalized human microglia cell lines also allow the establishment of in vitro models for high throughput and high content screening. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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