GCaMP3-Expressing Human Umbilical Vein Endothelial Cells
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Product Overview
Description
GCaMP3-Expressing Human Umbilical Vein Endothelial Cells (HUVECs) represent a significant advancement in the visualization and measurement of calcium signaling within endothelial cells.
These specialized cells allow researchers to observe dynamic changes in calcium levels, which are critical for various cellular functions. By employing GCaMP3, a genetically encoded calcium indicator, scientists can gain deeper insights into the intricate processes that govern endothelial physiology and its alterations during disease states.
Additionally, these cells are invaluable in the realm of drug discovery and mechanistic investigations, providing a platform for exploring treatments related to vascular health and disorders. This technology ultimately fosters a more comprehensive understanding of the roles endothelial cells play in both physiological and pathological contexts.
GCaMP3-expressing HUVECs provide a powerful tool for visualizing and quantifying calcium signaling in endothelial cells. Their use facilitates a better understanding of endothelial physiology and pathophysiology, and they are instrumental in drug discovery and mechanistic studies related to vascular health and disease.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0001-GCaMP3
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELLS CHARACTERIZATION
GCaMP3-expressing human umbilical vein endothelial cells (HUVECs) are genetically engineered endothelial cells that have been modified to express GCaMP3, a genetically encoded calcium indicator.
This allows for the real-time monitoring of intracellular calcium dynamics in living cells. These cells retain typical endothelial properties, including cobblestone morphology, expression of endothelial markers (such as CD31 and VE-cadherin), and the ability to form tubular networks.
Quick Facts
Product Type
Human Endothelial cells
Viability
>98% viable (Trypan Blue exclusion)
Applications
GCaMP3-expressing HUVECs are widely used in vascu…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
GCaMP3-expressing HUVECs are widely used in vascular biology and cell signaling research to study calcium signaling pathways. They enable high-resolution
Suitable for gcamp3-expressing huvecs are widely used in vascular biology and cell signaling research to study calcium signaling pathways. they enable high-resolution studies and research applications
non-invasive imaging of calcium flux in response to various stimuli
Suitable for non-invasive imaging of calcium flux in response to various stimuli studies and research applications
making them valuable for investigating endothelial function
Suitable for making them valuable for investigating endothelial function studies and research applications
mechanotransduction
Suitable for mechanotransduction studies and research applications
angiogenesis
Suitable for angiogenesis studies and research applications
and the effects of pharmacological agents on vascular cells.
Suitable for and the effects of pharmacological agents on vascular cells. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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