Human Synovial Microvascular Endothelial Cells
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Product Overview
Description
Human Synovial Microvascular Endothelial Cells (HSMECs) are primary endothelial cells derived from the microvasculature of the synovial tissue lining the joints. They are a specialized and biologically distinct cell population that plays a central role in joint vascular biology, immune cell trafficking, and the pathophysiology of inflammatory joint diseases such as rheumatoid arthritis (RA).
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0011
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELL CHARACTERIZATION
Expression of von Willebrand factor (vWF)
Metabolism of acetylated low-density lipoprotein (Ac-LDL)
Cytokine-inducible expression of adhesion molecules, including ICAM-1 (Intercellular Adhesion Molecule-1) and E-selectin (ELAM-1)
Quick Facts
Product Type
Human Endothelial Cells
Viability
>98% viable (Trypan Blue exclusion)
Applications
-Angiogenesis and neovascularization studies -Rh…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Angiogenesis and neovascularization studies -Rheumatoid arthritis and autoimmune joint disease research -Leukocyte-endothelial cell adhesion and transmigration assays -Vascular permeability and endothelial barrier function studies -Cytokine and inflammatory mediator response profiling
Suitable for -angiogenesis and neovascularization studies -rheumatoid arthritis and autoimmune joint disease research -leukocyte-endothelial cell adhesion and transmigration assays -vascular permeability and endothelial barrier function studies -cytokine and inflammatory mediator response profiling studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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