GFP Expressing Human Retinal Microvascular Endothelial Cells
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Product Overview
Description
GFP-Expressing Human Retinal Microvascular Endothelial Cells (HRMEC-GFP) are primary human retinal endothelial cells genetically modified to stably express Green Fluorescent Protein (GFP).
These cells retain the morphological, phenotypic, and functional characteristics of native retinal microvascular endothelial cells while providing a fluorescent marker for real-time visualization, cell tracking, migration studies, and angiogenesis research.
HRMEC-GFP cells are widely used as an in vitro model for studying retinal vascular biology, diabetic retinopathy, age-related macular degeneration (AMD), retinal neovascularization, blood-retinal barrier function, and drug screening applications.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP0018GFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELLS CHARACTERIZATION
-Stable expression of Green Fluorescent Protein (GFP)
-Typical endothelial cobblestone morphology
-Derived from human retinal microvasculature
-Positive for endothelial markers:
CD31 (PECAM-1)
VE-Cadherin (CD144)
von Willebrand Factor (vWF)
VEGFR-2 (KDR)
CD34
Uptake of acetylated LDL (Ac-LDL)
Formation of capillary-like tube structures in angiogenesis assays
Responsive to VEGF, TNF-?, hypoxia, and inflammatory stimuli
Suitable for live-cell imaging and fluorescence-based assays
Mycoplasma tested and negative
High GFP fluorescence stability through multiple passages
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viable (Post-thaw)
Applications
-Blood-Retinal Barrier Models Assessment of barr…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Blood-Retinal Barrier Models Assessment of barrier integrity Permeability and transport studies Cell-cell interaction studies with pericytes and retinal cells -Angiogenesis Studies Tube formation assays Endothelial migration and proliferation assays VEGF signaling pathway analysis Tissue Engineering Retinal organoid vascularization Vascular network formation in engineered tissues Regenerative medicine research
Suitable for -blood-retinal barrier models assessment of barrier integrity permeability and transport studies cell-cell interaction studies with pericytes and retinal cells -angiogenesis studies tube formation assays endothelial migration and proliferation assays vegf signaling pathway analysis tissue engineering retinal organoid vascularization vascular network formation in engineered tissues regenerative medicine research studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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