Plasma Membrane GFP Tagged Human Dermal Microvascular Endothelial Cells
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Product Overview
Description
Description
Plasma Membrane GFP-Tagged Human Dermal Microvascular Endothelial Cells are human endothelial cells derived from the small blood vessels of the skin and engineered to express green fluorescent protein localized to the plasma membrane. The GFP signal outlines the cell membrane, allowing clear visualization of cell borders, morphology, migration, cell–cell junctions, and vascular network formation in live-cell or fluorescence imaging studies.
These cells are useful for studying microvascular biology, angiogenesis, endothelial barrier function, inflammation, wound healing, and drug response in skin-related vascular models.
Key Features
Catalog Number: NBP-0005GFP-PM
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics
-Cell Type: Human Dermal Microvascular Endothelial Cells
-Fluorescent Tag: Plasma membrane-localized GFP
-Fluorescence: Green signal outlining the cell membrane
-Morphology :Cobblestone-like endothelial morphology under standard culture conditions
-Growth Pattern: Adherent cells
-Endothelial Markers: Typically positive for endothelial markers such as CD31, VE-Cadherin, vWF, and VEGFR2
Quick Facts
Product Type
Human Endothelial cells
Viability
>85% viable (Post-thaw)
Applications
1. Angiogenesis Research Used to study endotheli…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
1. Angiogenesis Research Used to study endothelial sprouting
Suitable for 1. angiogenesis research used to study endothelial sprouting studies and research applications
tube formation
Suitable for tube formation studies and research applications
vessel-like network development
Suitable for vessel-like network development studies and research applications
and responses to pro- or anti-angiogenic compounds. 2. Wound Healing Studies Useful for modeling dermal vascular repair
Suitable for and responses to pro- or anti-angiogenic compounds. 2. wound healing studies useful for modeling dermal vascular repair studies and research applications
endothelial migration
Suitable for endothelial migration studies and research applications
and cell–cell interactions during tissue regeneration. 3. Skin Inflammation Models Can be used to study endothelial activation
Suitable for and cell–cell interactions during tissue regeneration. 3. skin inflammation models can be used to study endothelial activation studies and research applications
leukocyte adhesion
Suitable for leukocyte adhesion studies and research applications
cytokine response
Suitable for cytokine response studies and research applications
and inflammatory signaling in dermal microvascular systems. 4. Drug Screening Suitable for testing compounds that affect endothelial viability
Suitable for and inflammatory signaling in dermal microvascular systems. 4. drug screening suitable for testing compounds that affect endothelial viability studies and research applications
permeability
Suitable for permeability studies and research applications
angiogenesis
Suitable for angiogenesis studies and research applications
toxicity
Suitable for toxicity studies and research applications
and vascular stability. 5. Live-Cell Imaging The plasma membrane GFP signal makes it easier to monitor cell shape
Suitable for and vascular stability. 5. live-cell imaging the plasma membrane gfp signal makes it easier to monitor cell shape studies and research applications
membrane remodeling
Suitable for membrane remodeling studies and research applications
junction organization
Suitable for junction organization studies and research applications
and cell movement over time. 6. 3D Vascular Models Can be incorporated into spheroids
Suitable for and cell movement over time. 6. 3d vascular models can be incorporated into spheroids studies and research applications
hydrogels
Suitable for hydrogels studies and research applications
organ-on-chip systems
Suitable for organ-on-chip systems studies and research applications
and tissue-engineered skin models to visualize microvascular structures.
Suitable for and tissue-engineered skin models to visualize microvascular structures. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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