RFP Conditionally Immortalized Human Glomerular Podocytes
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Product Overview
Description
RFP Conditionally Immortalized Human Glomerular Podocytes are a specialized line of human kidney podocyte cells that have been genetically engineered to express red fluorescent protein (RFP). This enhancement enables researchers to visually track and study these cells using fluorescence-based techniques, allowing for detailed imaging and live-cell analyses.
These innovative cells are invaluable for investigating the intricacies of the glomerular filtration barrier, understanding the processes of podocyte injury, exploring the underlying mechanisms of kidney diseases, and assessing how different drugs impact these vital functions in the kidneys. Their ability to maintain characteristic properties of native podocytes while providing a visual marker makes them a powerful tool in kidney research.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0064RFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Cell type: Human glomerular podocytes
Fluorescent marker: RFP / red fluorescent protein
Immortalization type: Conditional immortalization
Typical morphology: Epithelial-like to arborized/differentiated podocyte morphology under differentiation conditions
Relevant podocyte markers: nephrin, podocin, synaptopodin, WT1, podocalyxin, CD2AP, nestin
Quick Facts
Product Type
Immortalized Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Glomerular filtration barrier research -Podocyt…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Glomerular filtration barrier research -Podocyte injury and repair studies -Diabetic nephropathy and focal segmental glomerulosclerosis research -Nephrotoxicity screening -Drug-response assays -Fluorescence microscopy and live-cell tracking -Co-culture models with glomerular endothelial cells or mesangial cells -Kidney disease mechanism studies
Suitable for -glomerular filtration barrier research -podocyte injury and repair studies -diabetic nephropathy and focal segmental glomerulosclerosis research -nephrotoxicity screening -drug-response assays -fluorescence microscopy and live-cell tracking -co-culture models with glomerular endothelial cells or mesangial cells -kidney disease mechanism studies studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
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