Human Brain Microglia Cells
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Product Overview
Description
Human Brain Microglia Cells serve as a vital in vitro model for exploring immune activity within the human central nervous system. These specialized cells play a crucial role in various research areas, including the investigation of neuroinflammation, which is associated with various neurological disorders, and the underlying mechanisms of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
Additionally, they are integral to studying the brain's response to central nervous system injuries, their role in phagocytosis the process of engulfing and digesting cellular debris and the production of cytokines, which are important signaling molecules in the immune response. Furthermore, microglia cells are invaluable in the drug discovery process, aiding researchers in evaluating potential therapeutic agents. It is important to note that these cells are intended solely for research purposes and are not approved for diagnostic or therapeutic applications.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0040
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Microglia are a type of cell found in the human brain that resembles macrophages in both shape and immune-response behavior. They have the ability to perform phagocytosis, release cytokines, respond to inflammatory stimuli, and interact with neurons, astrocytes, endothelial cells, and other types of cells in the central nervous system (CNS).
Common markers used to identify microglia include Iba1, CD45, PU.1, CD11b, CX3CR1, TMEM119, and P2RY12, which can vary based on the source of the cells and the conditions in which they are cultured.
Quick Facts
Product Type
Human Non Endothelial cells
Viability
>98% viable (Trypan Blue exclusion)
Applications
-Blood–brain barrier and neuroimmune co-culture m…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Blood–brain barrier and neuroimmune co-culture models -Drug screening for anti-inflammatory and neuroprotective compounds -Toxicity testing for CNS-targeted therapeutics
Suitable for -blood–brain barrier and neuroimmune co-culture models -drug screening for anti-inflammatory and neuroprotective compounds -toxicity testing for cns-targeted therapeutics studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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