Human Dopaminergic Neuron Cells
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Product Overview
Description
Human dopaminergic neuron cells represent a vital and physiologically relevant model for exploring the intricate processes involved in dopamine neuron development, functionality, toxicity, and the underlying mechanisms of various diseases. These specialized cells are particularly valuable in neuroscience research, serving as key tools for modeling Parkinson's disease, investigating neuropharmacological responses, and conducting detailed high-content imaging studies.
They are distinguished by their expression of specific dopaminergic markers, which indicate their identity and functional potential. Additionally, their unique neuronal morphology is characterized by the presence of elongated neurites that extend outwards, facilitating intricate connections and network formation when cultured under optimal conditions. This ability to establish complex neuronal networks makes them essential for understanding the complex dynamics of the dopaminergic system.
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Key Features
Catalog Number: NBP-0057
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CHARACTERIZATION:
-Dopamine-producing neuronal phenotype
-Express dopaminergic markers such as Tyrosine Hydroxylase (TH), DAT, DDC, NURR1, and LMX1B
-Express general neuronal markers such as MAP2, III-tubulin/TUJ1, and NeuN
Quick Facts
Product Type
Human Non Endothelial cells
Viability
>90% viability post-thaw
Applications
-Parkinson’s disease research -Neurodegeneration…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Parkinson’s disease research -Neurodegeneration studies -Neurotoxicity screening -Drug discovery and compound testing -Dopamine signaling studies
Suitable for -parkinson’s disease research -neurodegeneration studies -neurotoxicity screening -drug discovery and compound testing -dopamine signaling studies studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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