Human Cardiac Myocytes (Adults)
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Product Overview
Description
Human Cardiac Myocytes, often referred to as adult human cardiomyocytes, are highly specialized contractile cells that are extracted from the tissue of adult human hearts. These remarkable cells play an essential role in the intricate process of heart muscle contraction, enabling the heart to pump blood effectively throughout the body.
Due to their unique properties and functions, they are vital for research in various fields, including cardiac physiology, where they help illuminate how the heart functions under normal and pathological conditions. Additionally, they are pivotal in investigating disease mechanisms, understanding the toxic effects of drugs, exploring the dynamics of electrical signaling in the heart (electrophysiology), and studying the processes involved in cardiomyocyte injury and subsequent repair. This makes them invaluable tools for advancing our understanding of heart health and disease.
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Key Features
Catalog Number: NBP-0048-AD
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Adult cardiac muscle phenotype
Contractile, striated morphology
Low proliferative capacity in culture
Express cardiomyocyte markers such as cardiac Troponin T/cTnT, cardiac Troponin I/cTnI, -actinin, myosin heavy chain, and connexin 43
Useful for mature cardiac cell studies compared with immature iPSC-derived cardiomyocytes
Quick Facts
Product Type
Human Non Endothelial cells
Viability
>85% viable (Post-thaw)
Applications
-Cardiotoxicity screening -Cardiovascular diseas…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Cardiotoxicity screening -Cardiovascular disease modeling -Drug discovery and safety testing -Electrophysiology and calcium-handling studies -Myocardial injury and ischemia research -Sarcomere organization and contractility studies -Co-culture models with fibroblasts
Suitable for -cardiotoxicity screening -cardiovascular disease modeling -drug discovery and safety testing -electrophysiology and calcium-handling studies -myocardial injury and ischemia research -sarcomere organization and contractility studies -co-culture models with fibroblasts studies and research applications
endothelial cells
Suitable for endothelial cells studies and research applications
or smooth muscle cells
Suitable for or smooth muscle cells studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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