Human A431 Epidermoid Carcinoma Cells
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Product Overview
Description
Human A431 cells are a type of adherent epithelial cell line that originates from human epidermoid carcinoma. They are extensively utilized in cancer biology and drug discovery due to their notable characteristics.
One of the key features of A431 cells is their high expression of the epidermal growth factor receptor (EGFR), which plays a critical role in cell signaling pathways that drive tumor growth and progression. This makes A431 cells an invaluable model for investigating various aspects of EGFR signaling, the biology of epithelial tumors, and the mechanisms regulating cell proliferation and apoptosis. Furthermore, these cells are instrumental in the evaluation of targeted anticancer therapies, enabling researchers to explore potential treatment options and understand the complexities of cancer at a cellular level.
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Key Features
Catalog Number: NBP-0066
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Species: Human
Cell type: Epidermoid carcinoma cells
Morphology: Adherent, epithelial-like
Growth pattern: Monolayer culture
Cancer type: Epidermoid / squamous carcinoma model
Notable marker: High EGFR expression
Quick Facts
Product Type
Tumor Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-EGFR signaling studies -Cancer drug screening a…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-EGFR signaling studies -Cancer drug screening and cytotoxicity assays -Tumor growth and apoptosis research -Epithelial carcinoma modeling -Immunofluorescence and biomarker validation -Xenograft and oncology research models
Suitable for -egfr signaling studies -cancer drug screening and cytotoxicity assays -tumor growth and apoptosis research -epithelial carcinoma modeling -immunofluorescence and biomarker validation -xenograft and oncology research models studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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