Human Pulmonary Microvascular Endothelial Cells
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Product Overview
Description
Human Pulmonary Microvascular Endothelial Cells (HPMECs) are primary endothelial cells derived from the small blood vessels of the human lung, especially the capillaries and microvasculature. They form the inner lining of pulmonary microvessels and are essential for maintaining the lung’s vascular barrier and proper gas exchange function.
These cells play a critical role in regulating vascular permeability, inflammation, immune cell migration, and blood–lung barrier integrity. Because of their physiological relevance, HPMECs are widely used in respiratory and vascular research, including studies on lung diseases such as acute respiratory distress syndrome (ARDS), pulmonary hypertension, fibrosis, and viral infections.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0032
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Morphology: Typical “cobblestone” endothelial monolayer in culture
Markers:
CD31 (PECAM-1)
VE-cadherin
vWF (von Willebrand factor)
Growth behavior: Contact-inhibited, forms tight monolayers
Barrier function: High relevance to vascular permeability studies
Origin: Human lung microvasculature (capillaries and small vessels)
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viability post-thaw
Applications
-Pulmonary disease modeling (ARDS, COPD, pulmonar…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Pulmonary disease modeling (ARDS
Suitable for -pulmonary disease modeling (ards studies and research applications
COPD
Suitable for copd studies and research applications
pulmonary hypertension). -Drug screening for vascular toxicity and permeability. -Inflammation research (cytokine signaling
Suitable for pulmonary hypertension). -drug screening for vascular toxicity and permeability. -inflammation research (cytokine signaling studies and research applications
leukocyte adhesion). -Angiogenesis studies. -COVID-19 and respiratory infection research. -Blood–lung barrier studies.
Suitable for leukocyte adhesion). -angiogenesis studies. -covid-19 and respiratory infection research. -blood–lung barrier studies. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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