RFP-Human Umbilical Artery Endothelial Cells (HUAECs)
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Product Overview
Description
RFP-Human Umbilical Artery Endothelial Cells (RFP-HUAECs) are primary human endothelial cells isolated from the umbilical artery and genetically modified to stably express Red Fluorescent Protein (RFP). These cells retain the typical morphology, phenotype, and biological functions of arterial endothelial cells while providing a fluorescent signal that enables real-time visualization and tracking in vitro and in vivo. RFP-HUAECs are widely used in vascular biology, angiogenesis research, and cell migration studies.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0113RFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CHARACTERISTICS:
-Stable expression of Red Fluorescent Protein (RFP) for live-cell imaging.
-Typical cobblestone morphology characteristic of endothelial cells.
-Positive expression of endothelial markers including:
-CD31 (PECAM-1)
-VE-Cadherin (CD144)
-von Willebrand Factor (vWF)
-eNOS (Endothelial Nitric Oxide Synthase)
-Ability to form capillary-like structures in angiogenesis assays.
-Responsive to angiogenic growth factors such as VEGF and FGF.
-Uptake of acetylated low-density lipoprotein (Ac-LDL).
-Suitable for fluorescence microscopy, flow cytometry, and co-culture experiments.
-Maintains arterial endothelial cell-specific functions and signaling pathways.
Quick Facts
Product Type
Human Endothelial cells
Viability
High viability
Applications
-Vascular Biology Research Investigation of endo…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Vascular Biology Research Investigation of endothelial cell physiology and arterial vascular function. Studies of endothelial barrier integrity and permeability. -Angiogenesis Studies Tube formation assays. Analysis of blood vessel development and remodeling. Evaluation of pro- and anti-angiogenic compounds. -Cell Tracking and Imaging Real-time monitoring of endothelial cell migration and proliferation. Visualization of cell-cell interactions in co-culture systems. Fluorescent tracking in tissue engineering and regenerative medicine models. -Cardiovascular Research Modeling arterial endothelial dysfunction. Investigation of atherosclerosis-related mechanisms. Assessment of vascular inflammation and oxidative stress. -Drug Discovery and Toxicology Screening of cardiovascular therapeutics. Evaluation of drug-induced endothelial toxicity. Testing of biomaterials and vascular implants. -Tissue Engineering Development of vascularized tissue constructs. Assessment of endothelialization on scaffolds and biomaterials. Studies of engineered blood vessel formation. -Advantages Bright and stable red fluorescence for long-term imaging. Eliminates the need for additional fluorescent staining. Facilitates high-content screening and automated image analysis. Compatible with multi-color fluorescence experiments using GFP
Suitable for -vascular biology research investigation of endothelial cell physiology and arterial vascular function. studies of endothelial barrier integrity and permeability. -angiogenesis studies tube formation assays. analysis of blood vessel development and remodeling. evaluation of pro- and anti-angiogenic compounds. -cell tracking and imaging real-time monitoring of endothelial cell migration and proliferation. visualization of cell-cell interactions in co-culture systems. fluorescent tracking in tissue engineering and regenerative medicine models. -cardiovascular research modeling arterial endothelial dysfunction. investigation of atherosclerosis-related mechanisms. assessment of vascular inflammation and oxidative stress. -drug discovery and toxicology screening of cardiovascular therapeutics. evaluation of drug-induced endothelial toxicity. testing of biomaterials and vascular implants. -tissue engineering development of vascularized tissue constructs. assessment of endothelialization on scaffolds and biomaterials. studies of engineered blood vessel formation. -advantages bright and stable red fluorescence for long-term imaging. eliminates the need for additional fluorescent staining. facilitates high-content screening and automated image analysis. compatible with multi-color fluorescence experiments using gfp studies and research applications
CFP
Suitable for cfp studies and research applications
or nuclear dyes. Provides a reliable model for studying human arterial endothelial cell behavior.
Suitable for or nuclear dyes. provides a reliable model for studying human arterial endothelial cell behavior. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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