ACE2-GFP Expressing Human Pulmonary Artery Endothelial Cells
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Product Overview
Description
ACE2-GFP Expressing Human Pulmonary Artery Endothelial cells serve as essential research tools for exploring the intricate role of ACE2 in maintaining vascular health and understanding various diseases. The incorporation of fluorescent labeling enables researchers to visualize the precise localization and function of ACE2 within these cells.
This facilitates in-depth investigations into how viruses enter cells, the responses of blood vessels to different stimuli, and the development of targeted therapeutic interventions aimed at modulating ACE2 pathways to improve vascular health. These studies hold significant potential for advancing our understanding of disease mechanisms and enhancing treatment strategies in cardiovascular medicine.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0120ACE2-GFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELLS CHARACTERIZATION
-These are human pulmonary artery endothelial cells genetically modified to express ACE2 (Angiotensin-Converting Enzyme 2) fused with GFP (Green Fluorescent Protein).
-The GFP tag allows for visualization and tracking of ACE2 expression in live cells via fluorescence microscopy.
-The cells maintain typical endothelial cell morphology and function, with added capacity for direct observation of ACE2 localization and dynamics.
Quick Facts
Product Type
Human GFP
Viability
>98% viable (Trypan Blue exclusion)
Applications
-Used to study ACE2’s role in vascular biology an…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Used to study ACE2’s role in vascular biology and pathophysiology
Suitable for -used to study ace2’s role in vascular biology and pathophysiology studies and research applications
particularly in the context of pulmonary diseases and COVID-19
Suitable for particularly in the context of pulmonary diseases and covid-19 studies and research applications
where ACE2 serves as the entry receptor for SARS-CoV-2. -Enable real-time monitoring of ACE2 trafficking
Suitable for where ace2 serves as the entry receptor for sars-cov-2. -enable real-time monitoring of ace2 trafficking studies and research applications
expression patterns
Suitable for expression patterns studies and research applications
and interaction with viral proteins or pharmacological agents. -Useful in drug screening for molecules that modulate ACE2 expression or function.
Suitable for and interaction with viral proteins or pharmacological agents. -useful in drug screening for molecules that modulate ace2 expression or function. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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