Human Lung Airway Smooth Muscle Cells
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Product Overview
Description
Human Lung Airway Smooth Muscle Cells (HLASMCs) are primary smooth muscle cells isolated from human airway tissue. These cells play a critical role in regulating airway tone, bronchoconstriction, and respiratory function.
HLASMCs are widely used in respiratory disease research, including asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and airway remodeling studies. They exhibit the characteristic spindle-shaped morphology typical of smooth muscle cells and express key smooth muscle markers such as -Smooth Muscle Actin (-SMA), SM22,Calponin, and Smooth Muscle Myosin Heavy Chain (SM-MHC).
Key Features
Catalog Number: NBP-0121
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Marker Expression:
Positive: -SMA, Calponin, SM22, Desmin, SM-MHC
Negative: CD31, Cytokeratin, CD45
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viable (Post-thaw)
Applications
-Asthma and COPD research. -Airway remodeling an…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Asthma and COPD research. -Airway remodeling and fibrosis studies. -Bronchoconstriction and airway hyperresponsiveness assays. -Drug discovery and toxicology testing. -Inflammatory signaling pathway analysis. -Cell-cell interaction studies with epithelial or immune cells. -Extracellular matrix (ECM) remodeling research. -Pulmonary disease modeling.
Suitable for -asthma and copd research. -airway remodeling and fibrosis studies. -bronchoconstriction and airway hyperresponsiveness assays. -drug discovery and toxicology testing. -inflammatory signaling pathway analysis. -cell-cell interaction studies with epithelial or immune cells. -extracellular matrix (ecm) remodeling research. -pulmonary disease modeling. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
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