Human Bone Marrow-Derived Endothelial Cells
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Product Overview
Description
Human Bone Marrow-Derived Endothelial Cells (BMECs) represent a unique and specialized subset of endothelial cells that are extracted from human bone marrow. These cells are crucial in forming the inner lining of blood vessels, where they serve as a dynamic barrier between circulating blood and surrounding tissues.
BMECs are integral to several physiological processes, such as vascular biology, where they contribute to the regulation of blood flow and the maintenance of vascular homeostasis. Their role in hematopoiesis is particularly important, as they provide a supportive microenvironment for the development and differentiation of blood cells. Additionally, BMECs are actively involved in tissue regeneration, participating in repair mechanisms following injury by promoting angiogenesis, the formation of new blood vessels from existing ones.
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Key Features
Catalog Number: NBP-0210
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELLS CHARACTERIZATION
-Express typical endothelial markers (e.g., CD31, VE-cadherin, vWF, CD146).
-Exhibit cobblestone morphology in culture.
-Capable of forming capillary-like structures (tube formation assay).
-Support angiogenesis and vascular remodeling.
-Respond to angiogenic growth factors (e.g., VEGF, bFGF).
-Can interact with hematopoietic stem cells and support their maintenance.
-Low immunogenicity compared to other endothelial sources.
Quick Facts
Product Type
Human Endothelial cells
Viability
>98% viable (Trypan Blue exclusion)
Applications
-Vascular tissue engineering and regenerative med…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Vascular tissue engineering and regenerative medicine. -Study of angiogenesis and vasculogenesis in vitro. -Models for blood vessel formation and function. -Cell-based therapies for ischemic diseases (e.g.
Suitable for -vascular tissue engineering and regenerative medicine. -study of angiogenesis and vasculogenesis in vitro. -models for blood vessel formation and function. -cell-based therapies for ischemic diseases (e.g. studies and research applications
myocardial infarction
Suitable for myocardial infarction studies and research applications
peripheral artery disease). -Co-culture systems to support hematopoietic stem cell expansion. -Drug screening for angiogenic or anti-angiogenic compounds. -Research on endothelial dysfunction and vascular pathologies.
Suitable for peripheral artery disease). -co-culture systems to support hematopoietic stem cell expansion. -drug screening for angiogenic or anti-angiogenic compounds. -research on endothelial dysfunction and vascular pathologies. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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