3D Human Blood–Brain Barrier Model
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Product Overview
Description
The 3D Human Blood–Brain Barrier Model is an advanced in vitro co-culture system designed to mimic key structural and functional properties of the human blood–brain barrier. The model is generated using human brain microvascular endothelial cells, human brain pericytes, and human brain astrocytes arranged in an insert-based format to support endothelial polarization, tight junction formation, and physiologically relevant barrier function.
This model is designed for studying BBB permeability, transporter activity, receptor-mediated transcytosis, endothelial barrier integrity, CNS drug delivery, BBB toxicology, and disease-related barrier disruption.
Key Features
Product Name: 3D Human Blood–Brain Barrier Model
Catalog Number: NEO3DHB-12
Format: 12-well, insert-based model
Product Type: Human in vitro BBB co-culture model
Storage: Store frozen model at -80°C until ready for use
Media Storage: Store supplied media at or below -20°C
Recommended Use Window: Day 4 to Day 7 after thawing/activation
For Research Use Only
Quick Facts
Product Type
3D Tissue Model
Viability
High viability
Applications
• Drug BBB permeability assays • CNS drug deli…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
• Drug BBB permeability assays • CNS drug delivery studies • Blood-to-brain transport studies • BBB physiology research • BBB toxicology studies • Brain endothelial toxicity assays • Disease modeling • Cell-cell interaction studies • Transport pathway modulation studies • Receptor-ligand interaction studies • Endocytosis and transcytosis studies • Paracellular barrier studies • Tight junction protein expression and localization studies • Microbial pathogenesis studies involving viruses
Suitable for • drug bbb permeability assays • cns drug delivery studies • blood-to-brain transport studies • bbb physiology research • bbb toxicology studies • brain endothelial toxicity assays • disease modeling • cell-cell interaction studies • transport pathway modulation studies • receptor-ligand interaction studies • endocytosis and transcytosis studies • paracellular barrier studies • tight junction protein expression and localization studies • microbial pathogenesis studies involving viruses studies and research applications
bacteria
Suitable for bacteria studies and research applications
or parasites • Neuroimmune target compound screening
Suitable for or parasites • neuroimmune target compound screening studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
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