Cre-expressing Human Primary Brain Vascular Fibroblasts
Quick Actions
Documentation 0 files
Product Overview
Description
Cre-Expressing Human Primary Brain Vascular Fibroblasts are specialized cells derived from the vascular structures of human brain tissue. These fibroblasts are genetically modified to express Cre recombinase, facilitating targeted genetic manipulation in research. They play a crucial role in maintaining the structural integrity and function of blood vessels in the brain and are important for studying neurovascular interactions, brain pathologies, and the blood-brain barrier.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-1985Cre
Product Format: Frozen
Passage:1(P1)
Vial Cell Number: > 5x10[5]
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization
Cells are characterized by their spindle morphology and immunofluorescent staining with anti-fibroblast-specific protein 1 or anti-Vimentin antibody .
Growth Conditions: 37°C, 5% CO2 .
Culture Guidance: Cells can typically be expanded for 3-5 passages at a split ratio of 1:2. Repeated freezing and thawing is not recommended .
Quantity: Each vial contains >5 × 10 cells or 0.5 × 10? cells in 1 ml volume.
Quick Facts
Product Type
Cre-Expressing Human Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
Gene knockout studies utilizing the Cre-loxP syst…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Gene knockout studies utilizing the Cre-loxP system - Investigations into the role of fibroblasts in brain diseases such as stroke and neurodegeneration - Assessment of extracellular matrix dynamics and their impact on vascular health
Suitable for gene knockout studies utilizing the cre-loxp system - investigations into the role of fibroblasts in brain diseases such as stroke and neurodegeneration - assessment of extracellular matrix dynamics and their impact on vascular health studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
Contact Support
