GFP Expressing Human Glomerular Microvascular Endothelial Cells
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Product Overview
Description
GFP-expressing Human Glomerular Microvascular Endothelial cells are specialized primary endothelial cells derived from the intricate network of blood vessels within the glomeruli of the kidneys.
These cells have been genetically modified to continuously express green fluorescent protein, which allows them to emit a vivid green glow under specific lighting conditions. This unique characteristic facilitates the direct observation of various processes, including the structural morphology of the endothelium, cell growth dynamics, migration patterns, and the intricate development of vascular networks in real time. By using these cells, researchers can gain valuable insights into endothelial function and behavior in a live cellular environment.
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Key Features
Catalog Number: NBP-0004GFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
They display endothelial morphology with a cobblestone-like appearance and express key endothelial markers such as CD31, VE-Cadherin, and von Willebrand factor. GFP expression enables fluorescence-based tracking without additional staining. These cells are suitable for studying kidney microvascular biology, filtration barrier function, angiogenesis, and endothelial responses to inflammatory or toxic stimuli.
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viability post-thaw
Applications
Used in renal vascular research, diabetic nephrop…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Used in renal vascular research
Suitable for used in renal vascular research studies and research applications
diabetic nephropathy studies
Suitable for diabetic nephropathy studies studies and research applications
kidney disease modeling
Suitable for kidney disease modeling studies and research applications
angiogenesis assays
Suitable for angiogenesis assays studies and research applications
permeability assays
Suitable for permeability assays studies and research applications
drug screening
Suitable for drug screening studies and research applications
inflammation studies
Suitable for inflammation studies studies and research applications
endothelial injury models
Suitable for endothelial injury models studies and research applications
and live-cell imaging. They are also useful for co-culture systems with podocytes
Suitable for and live-cell imaging. they are also useful for co-culture systems with podocytes studies and research applications
mesangial cells
Suitable for mesangial cells studies and research applications
or renal epithelial cells to model the glomerular filtration barrier.
Suitable for or renal epithelial cells to model the glomerular filtration barrier. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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