GFP Human Retinal Microvascular Endothelial Cells
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Product Overview
Description
GFP Human Retinal Microvascular Endothelial Cells are specialized primary cells derived from the intricate network of blood vessels in the retina. These cells have been genetically engineered to produce Green Fluorescent Protein (GFP), enabling them to fluoresce under specific light conditions.
This unique characteristic makes them particularly useful for visualizing and studying various physiological and pathological processes. Researchers employ these cells to investigate crucial aspects such as the functionality of the blood-retinal barrier, the mechanisms of angiogenesis (the formation of new blood vessels), and changes in vascular permeability that can occur in response to inflammatory conditions.
Additionally, they play a significant role in examining the underlying mechanisms associated with diabetic retinopathy, a common complication of diabetes that affects retinal health.
Key Features
Catalog Number: NBP-GFP-HRME-001
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
-Express GFP, allowing live-cell tracking and fluorescence imaging
-Exhibit endothelial morphology with a cobblestone-like appearance
-Positive for endothelial markers such as CD31, VE-Cadherin, von Willebrand Factor, and VEGFR2
-Capable of forming tube-like structures in angiogenesis assays
-Useful for studying retinal vascular biology and microvascular dysfunction
-Suitable for fluorescence microscopy, live-cell imaging, and co-culture models
Quick Facts
Product Type
Human Endothelial cells
Viability
>85% viable (Post-thaw)
Applications
-Retinal angiogenesis research -Diabetic retinop…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Retinal angiogenesis research -Diabetic retinopathy studies -Blood-retinal barrier models -Drug screening and toxicity testing -Vascular permeability assays -Inflammation and cytokine response studies -Endothelial cell migration and tube formation assays -Live-cell tracking using GFP fluorescence
Suitable for -retinal angiogenesis research -diabetic retinopathy studies -blood-retinal barrier models -drug screening and toxicity testing -vascular permeability assays -inflammation and cytokine response studies -endothelial cell migration and tube formation assays -live-cell tracking using gfp fluorescence studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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