Human Colon Cancer-Associated Endothelial Cells
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Product Overview
Description
Human colon cancer-associated endothelial cells are a critical component in understanding the tumor microenvironment and the development of colon cancer. These endothelial cells acquire specific characteristics that support tumor growth and metastasis.
In tumor-associated endothelial cells, several changes occur, such as enhanced permeability, increased expression of adhesion molecules, and the production of various growth factors like VEGF (vascular endothelial growth factor). This adaptation allows for more efficient nutrient supply to the tumor while promoting angiogenesis the formation of new blood vessels.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPCAE002
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Positive for endothelial cell markers such as CD31 (PECAM-
1) and VE-Cadherin, as verified by immunofluorescence staining or flow cytometry (FACS). Uptake of DiI-Ac-LDL (acetylated low-density lipoprotein) as a functional marker .
Quick Facts
Product Type
Human Cancer Associated Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
• Cell adhesion and cell-to-cell adhesion assays.…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
• Cell adhesion and cell-to-cell adhesion assays. • Cell migration studies. • In vitro vascular tube formation assays. • Standard biochemical procedures: RT-PCR
Suitable for • cell adhesion and cell-to-cell adhesion assays. • cell migration studies. • in vitro vascular tube formation assays. • standard biochemical procedures: rt-pcr studies and research applications
Western blotting
Suitable for western blotting studies and research applications
immunoprecipitation. • Immunofluorescent staining and flow cytometry.
Suitable for immunoprecipitation. • immunofluorescent staining and flow cytometry. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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