Human Parathyroid Microvascular Endothelial Cells (HPaTMVECs)
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Product Overview
Description
Human Parathyroid Microvascular Endothelial Cells are specialized endothelial cells isolated from the microvasculature of the human parathyroid gland. These cells form the inner lining of small blood vessels and capillaries that support parathyroid tissue by delivering oxygen, nutrients, hormones, and signaling molecules.
HPMECs play a critical role in maintaining vascular homeostasis and facilitating the secretion and transport of parathyroid hormone (PTH), which regulates calcium and phosphate metabolism throughout the body.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0219
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Morphology
Typical cobblestone-shaped appearance when cultured to confluence.
Form tightly connected monolayers.
Exhibit contact inhibition under normal growth conditions.
Surface Markers
Common endothelial markers include:
CD31 (PECAM-1)
VE-Cadherin (CD144)
von Willebrand Factor (vWF)
CD34
Endothelial Nitric Oxide Synthase (eNOS)
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viability post-thaw
Applications
Endocrine Research Study of parathyroid gland va…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Endocrine Research Study of parathyroid gland vascular biology. Investigation of hormone secretion and transport mechanisms. Analysis of vascular-endocrine interactions. Angiogenesis Studies Evaluation of new blood vessel formation. Screening of pro-angiogenic and anti-angiogenic compounds. Assessment of endothelial migration and proliferation. Disease Modeling Hyperparathyroidism research. Hypoparathyroidism studies. Investigation of parathyroid adenoma-associated vascular changes. Drug Discovery and Toxicology Testing vascular effects of novel therapeutics. Evaluation of endocrine-targeting compounds. Assessment of endothelial toxicity and vascular safety. Tissue Engineering Development of vascularized endocrine tissue models. Construction of 3D parathyroid organoid systems. Regenerative medicine applications.
Suitable for endocrine research study of parathyroid gland vascular biology. investigation of hormone secretion and transport mechanisms. analysis of vascular-endocrine interactions. angiogenesis studies evaluation of new blood vessel formation. screening of pro-angiogenic and anti-angiogenic compounds. assessment of endothelial migration and proliferation. disease modeling hyperparathyroidism research. hypoparathyroidism studies. investigation of parathyroid adenoma-associated vascular changes. drug discovery and toxicology testing vascular effects of novel therapeutics. evaluation of endocrine-targeting compounds. assessment of endothelial toxicity and vascular safety. tissue engineering development of vascularized endocrine tissue models. construction of 3d parathyroid organoid systems. regenerative medicine applications. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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