Human Primary Diabetic Pulmonary Vein Endothelial Cells
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Product Overview
Description
Human Primary Diabetic Pulmonary Vein Endothelial Cells (DPVEC) are isolated from the pulmonary vein associated with Type 2 Diabetes Mellitus. These cells exhibit venous endothelial characteristics with diabetic dysfunction, suitable for studying pulmonary venous complications of diabetes and endothelial dysfunction.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPD016
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Positive for endothelial markers: - Positive for endothelial cell
markers: CD31 (PECAM-1) and VE-Cadherin by
immunofluorescence staining or FACS .
- Cells are pre-coated with PECAM-1 antibody during isolation using magnetic beads .
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Diabetic Vasculopathy: Investigating mechanisms …
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Diabetic Vasculopathy: Investigating mechanisms of endothelial dysfunction caused by hyperglycemia. -Pulmonary Disease Modeling: Studying the role of the venous endothelium in diabetic complications such as pulmonary hypertension or acute lung injury. -Drug Discovery: Screening compounds for their ability to reverse endothelial dysfunction (e.g.
Suitable for -diabetic vasculopathy: investigating mechanisms of endothelial dysfunction caused by hyperglycemia. -pulmonary disease modeling: studying the role of the venous endothelium in diabetic complications such as pulmonary hypertension or acute lung injury. -drug discovery: screening compounds for their ability to reverse endothelial dysfunction (e.g. studies and research applications
improving Nitric Oxide bioavailability
Suitable for improving nitric oxide bioavailability studies and research applications
reducing oxidative stress). -Vascular Biology: Assessing permeability
Suitable for reducing oxidative stress). -vascular biology: assessing permeability studies and research applications
angiogenesis
Suitable for angiogenesis studies and research applications
and leukocyte adhesion in a disease-relevant context.
Suitable for and leukocyte adhesion in a disease-relevant context. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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