Human Pulmonary Artery Endothelial Cells (HPuAECs)
Quick Actions
Documentation 0 files
Product Overview
Description
Human Pulmonary Artery Endothelial Cells (HPuAECs) are specialized vascular endothelial cells that line the inner surface of the pulmonary arteries, which carry deoxygenated blood from the heart to the lungs. They play a central role in regulating vascular tone, blood flow, and lung-specific vascular function.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0120
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
HPuAECs share general endothelial features but have lung- and pulmonary-artery–specific properties:
-Markers: CD31 (PECAM-1), VE-cadherin, von Willebrand factor (vWF), eNOS.
-Morphology: Polygonal “cobblestone” monolayer in culture.
-Function: Barrier formation, vasodilation/vasoconstriction regulation.
-High responsiveness to shear stress and oxygen tension changes.
-Nitric oxide production via eNOS activity is especially important in pulmonary circulation.
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viability post-thaw
Applications
-Pulmonary hypertension studies -Drug screening …
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Pulmonary hypertension studies -Drug screening for cardiovascular and lung diseases -Angiogenesis and vascular biology research -Inflammation and endothelial dysfunction models -Toxicology testing (airborne particles
Suitable for -pulmonary hypertension studies -drug screening for cardiovascular and lung diseases -angiogenesis and vascular biology research -inflammation and endothelial dysfunction models -toxicology testing (airborne particles studies and research applications
drugs
Suitable for drugs studies and research applications
pollutants) -Gene expression and signaling pathway studies (e.g.
Suitable for pollutants) -gene expression and signaling pathway studies (e.g. studies and research applications
NO signaling
Suitable for no signaling studies and research applications
VEGF pathways)
Suitable for vegf pathways) studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
Contact SupportDocumentation & Resources
No Documentation Available
Documentation for this product is not yet available.
Request Documentation
