Human Pulmonary Artery Smooth Muscle Cells
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Product Overview
Description
Human pulmonary artery smooth muscle cells are specialized cells derived from the smooth muscle layer of the pulmonary artery. These cells play a vital role in understanding the complex dynamics of pulmonary vascular biology. They are involved in various physiological processes, including the contraction and relaxation of blood vessels, structural remodeling in response to injury or stress, and the inflammatory responses that can occur in the pulmonary circulation.
Research on these cells is essential for exploring the underlying mechanisms of diseases that impact the pulmonary vascular system, such as pulmonary hypertension and other disorders affecting blood flow and pressure within the lungs.
Key Features
Catalog Number: NBP-0101
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
HPASMCs typically show spindle-shaped morphology and express smooth muscle markers such as:
-SMA, SM22, calponin, and smooth muscle myosin heavy chain.
They are commonly used because they closely represent the behavior of native pulmonary artery smooth muscle cells in vitro.
Quick Facts
Product Type
Human Smooth Muscle Cells
Viability
>90% viability post-thaw
Applications
Pulmonary hypertension Vascular remodeling Smoo…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Pulmonary hypertension Vascular remodeling Smooth muscle contraction studies Drug screening Inflammation and fibrosis research Hypoxia-induced vascular disease Endothelial–smooth muscle interaction studies 3D vascular models and co-culture systems
Suitable for pulmonary hypertension vascular remodeling smooth muscle contraction studies drug screening inflammation and fibrosis research hypoxia-induced vascular disease endothelial–smooth muscle interaction studies 3d vascular models and co-culture systems studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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