Human Uterine Microvascular Endothelial Cells
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Product Overview
Description
Human Uterine Microvascular Endothelial Cells (HUtMECs) are primary endothelial cells derived from the microvasculature of the human uterus. They line the small blood vessels (capillaries and microvessels) within uterine tissue and play a key role in regulating blood flow, vascular permeability, and angiogenesis in the endometrial environment.
These cells are essential for studying uterine vascular biology, especially in processes such as the menstrual cycle, implantation, pregnancy, and endometrial remodeling.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0023
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
-Cell type: Primary microvascular endothelial cells
-Origin: Human uterine tissue (endometrial microvasculature)
-Morphology: Spindle-shaped or cobblestone monolayer when confluent
-Markers: Commonly express CD31 (PECAM-1), CD144 (VE-cadherin), vWF
Functionality:
-Form capillary-like networks in vitro
-Respond to angiogenic factors such as VEGF
-High barrier and permeability regulation activity
-Growth behavior: Requires specialized endothelial growth media; limited passage lifespan compared to immortalized lines
Quick Facts
Product Type
Human Endothelial cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Angiogenesis research (uterine vascular formatio…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Angiogenesis research (uterine vascular formation and remodeling) -Reproductive biology studies (implantation and endometrial receptivity) -Gynecological disease modeling (endometriosis
Suitable for -angiogenesis research (uterine vascular formation and remodeling) -reproductive biology studies (implantation and endometrial receptivity) -gynecological disease modeling (endometriosis studies and research applications
uterine fibroids
Suitable for uterine fibroids studies and research applications
infertility) -Drug screening & toxicity testing targeting vascular effects -Hormonal regulation studies (estrogen and progesterone effects on uterine vasculature) -Inflammation and vascular permeability research
Suitable for infertility) -drug screening & toxicity testing targeting vascular effects -hormonal regulation studies (estrogen and progesterone effects on uterine vasculature) -inflammation and vascular permeability research studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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