Immortalized Human Brain Microvascular Endothelial Cells (HBMEC)
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Product Overview
Description
Primary Human Brain Microvascular Endothelial Cells (HBMEC) immortalized via lentiviral transduction with SV40 Large T antigen and hTERT. These cells retain key phenotypic and functional characteristics of the Blood-Brain Barrier (BBB) including high transendothelial electrical resistance (TEER) and expression of efflux transporters. Ideal for neuroinflammation studies, drug transport assays, and stroke research.
Key Features
Catalog Number: NBP-IHEC02
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viable (Post-thaw)
Applications
Applications • Blood-Brain Barrier (BBB) modelin…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Applications • Blood-Brain Barrier (BBB) modeling • Drug permeability screening (P-gp substrates) • Transmigration assays (Neutrophils/Monocytes) • Hypoxia/reperfusion injury studies
Suitable for applications • blood-brain barrier (bbb) modeling • drug permeability screening (p-gp substrates) • transmigration assays (neutrophils/monocytes) • hypoxia/reperfusion injury studies studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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