Plasma Membrane GFP Tagged Human Pulmonary Microvascular Endothelial Cells
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Product Overview
Description
Plasma Membrane GFP-Tagged Human Pulmonary Microvascular Endothelial Cells are human lung microvascular endothelial cells engineered to express green fluorescent protein localized to the plasma membrane. These cells allow clear visualization of cell borders, morphology, cell–cell junction organization, migration, and endothelial network formation under fluorescence microscopy.
These cells are useful for studying the pulmonary microvasculature, endothelial barrier function, angiogenesis, inflammation, vascular permeability, and drug response in lung-related research models.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0032GFP-PM
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics
Cell Type: Human Pulmonary Microvascular Endothelial Cells
Fluorescent Tag: GFP targeted to the plasma membrane
Fluorescence: Green signal outlining the cell membrane
Morphology: Cobblestone-like endothelial morphology under normal culture conditions
Markers: Common endothelial markers may include CD31, VE-Cadherin, vWF, and VEGFR2
Growth Pattern: Adherent monolayer culture
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viable (Post-thaw)
Applications
1. Endothelial Barrier Function Studies Useful f…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
1. Endothelial Barrier Function Studies Useful for evaluating cell–cell contact
Suitable for 1. endothelial barrier function studies useful for evaluating cell–cell contact studies and research applications
monolayer integrity
Suitable for monolayer integrity studies and research applications
vascular permeability
Suitable for vascular permeability studies and research applications
and disruption of endothelial barriers. 2. Pulmonary Vascular Research Ideal for studying lung microvascular biology
Suitable for and disruption of endothelial barriers. 2. pulmonary vascular research ideal for studying lung microvascular biology studies and research applications
pulmonary inflammation
Suitable for pulmonary inflammation studies and research applications
pulmonary edema
Suitable for pulmonary edema studies and research applications
ARDS-related endothelial injury
Suitable for ards-related endothelial injury studies and research applications
and vascular remodeling. 3. Live-Cell Imaging The plasma membrane GFP signal allows real-time visualization of cell shape
Suitable for and vascular remodeling. 3. live-cell imaging the plasma membrane gfp signal allows real-time visualization of cell shape studies and research applications
migration
Suitable for migration studies and research applications
spreading
Suitable for spreading studies and research applications
and junctional organization. 4. Angiogenesis and Tube Formation Assays Can be used to monitor endothelial network formation
Suitable for and junctional organization. 4. angiogenesis and tube formation assays can be used to monitor endothelial network formation studies and research applications
branching
Suitable for branching studies and research applications
and cell–cell interactions in 2D or 3D angiogenesis models. 5. Drug Screening and Toxicity Testing Useful for evaluating compounds that affect endothelial morphology
Suitable for and cell–cell interactions in 2d or 3d angiogenesis models. 5. drug screening and toxicity testing useful for evaluating compounds that affect endothelial morphology studies and research applications
vascular integrity
Suitable for vascular integrity studies and research applications
inflammation
Suitable for inflammation studies and research applications
or pulmonary endothelial toxicity. 6. Co-Culture Models Can be used with epithelial cells
Suitable for or pulmonary endothelial toxicity. 6. co-culture models can be used with epithelial cells studies and research applications
fibroblasts
Suitable for fibroblasts studies and research applications
immune cells
Suitable for immune cells studies and research applications
pericytes
Suitable for pericytes studies and research applications
or smooth muscle cells to create lung vascular microenvironment models.
Suitable for or smooth muscle cells to create lung vascular microenvironment models. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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