Human Ovarian Cancer-Associated Endothelial Cells
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Product Overview
Description
Human Ovarian Cancer-Associated Endothelial Cells are a genomically and functionally distinct population that are
co-opted and reprogrammed by the tumor to support angiogenesis, immune evasion, and metastatic spread.
Their complex interactions within the tumor microenvironment governed by VEGF and a range of alternative pro-angiogenic mediators make them both a key driver of disease progression and a compelling target for novel therapeutic strategies. Advances in single-cell transcriptomics, 3D organoid models, and organ-on-a-chip technologies are continuing to deepen our understanding of their biology and clinical relevance.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPCAE002
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Positive for endothelial cell markers such as CD31 (PECAM-
1) and VE-Cadherin, as verified by immunofluorescence staining or flow cytometry (FACS). Uptake of DiI-Ac-LDL (acetylated low-density lipoprotein) as a functional marker .
Quick Facts
Product Type
Human Cancer Associated Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
- Cell Adhesion and Migration Assays -Vascular T…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
- Cell Adhesion and Migration Assays -Vascular Tube Formation Assays (Angiogenesis) -Co-culture Experiments to study tumor-stromal interactions -Gene Expression Analysis (e.g.
Suitable for - cell adhesion and migration assays -vascular tube formation assays (angiogenesis) -co-culture experiments to study tumor-stromal interactions -gene expression analysis (e.g. studies and research applications
RT-PCR) -Protein Expression Analysis (e.g.
Suitable for rt-pcr) -protein expression analysis (e.g. studies and research applications
Western blotting
Suitable for western blotting studies and research applications
Immunoprecipitation) - Immunofluorescent Staining and Flow Cytometry - General research on endothelial cell biology and vascular diseases
Suitable for immunoprecipitation) - immunofluorescent staining and flow cytometry - general research on endothelial cell biology and vascular diseases studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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