Human Ovarian Metastatic Cancer-Associated Endothelial Cells
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Product Overview
Description
Human Ovarian Metastatic Cancer-Associated Endothelial Cells are not passive bystanders but active drivers of tumor progression, metastasis, and immune evasion. Their unique molecular and functional properties including extensive gene alterations, heightened pro-angiogenic activity, enhanced vascular permeability, and immune checkpoint expression distinguish them from normal endothelial cells and make them compelling therapeutic targets.
A deeper understanding of TEC biology, particularly through emerging single-cell and multi-omic approaches, holds promise for developing more effective and durable treatments for this devastating disease.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPCAE007
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Positive for endothelial cell markers such as CD31 (PECAM-
1) and VE-Cadherin, as verified by immunofluorescence staining or flow cytometry (FACS). Uptake of DiI-Ac-LDL (acetylated low- density lipoprotein) as a functional marker .
Quick Facts
Product Type
Human Cancer Associated Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Cell Adhesion and Migration Assays -Vascular Tu…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Cell Adhesion and Migration Assays -Vascular Tube Formation Assays (Angiogenesis) - Co-culture Experiments to study tumor-stromal interactions - Gene Expression Analysis (e.g.
Suitable for -cell adhesion and migration assays -vascular tube formation assays (angiogenesis) - co-culture experiments to study tumor-stromal interactions - gene expression analysis (e.g. studies and research applications
RT-PCR) - Protein Expression Analysis (e.g.
Suitable for rt-pcr) - protein expression analysis (e.g. studies and research applications
Western blotting
Suitable for western blotting studies and research applications
Immunoprecipitation) - Immunofluorescent Staining and Flow Cytometry - General research on endothelial cell biology and vascular diseases
Suitable for immunoprecipitation) - immunofluorescent staining and flow cytometry - general research on endothelial cell biology and vascular diseases studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
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