Human Placental Microvascular Pericytes
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Product Overview
Description
Human Placental Microvascular Pericytes are specialized, multifunctional support cells that reside in the perivascular regions surrounding the capillaries and small blood vessels within the placenta. These remarkable cells are integral to maintaining the structural integrity and stability of the microvascular network.
They provide essential support to endothelial cells the cells lining the blood vessels and play a pivotal role in the processes of angiogenesis, which is the formation of new blood vessels, and the maturation of the placental vasculature.
The development of intricate vascular branching and the efficient angiogenesis in the placenta are vital for facilitating the exchange of nutrients and waste products between the mother and fetus. This intricate exchange is crucial for fetal growth and development. As key contributors to this process, pericytes work in concert with endothelial cells to ensure healthy vessel growth and stability, ultimately supporting the overall functionality of the placental microenvironment.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0029
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
These cells typically show pericyte-associated markers such as PDGFR, NG2/CSPG4, -SMA/ACTA2, Nestin, and often CD146 in placental perivascular populations.
Quick Facts
Product Type
Human Endothelial cells
Viability
>98% viable (Trypan Blue exclusion)
Applications
Research in placental angiogenesis, vascular remo…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Research in placental angiogenesis
Suitable for research in placental angiogenesis studies and research applications
vascular remodeling
Suitable for vascular remodeling studies and research applications
the maternal-fetal interface
Suitable for the maternal-fetal interface studies and research applications
preeclampsia
Suitable for preeclampsia studies and research applications
and fetal growth restriction is significantly enriched by studying placental pericytes. They have also been examined in human 3D microvascular models related to vascular dysfunction.
Suitable for and fetal growth restriction is significantly enriched by studying placental pericytes. they have also been examined in human 3d microvascular models related to vascular dysfunction. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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