Human Lung Airway Smooth Muscle Cells Expressing AEQGFP in Mitochondria
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Product Overview
Description
Human Lung Airway Smooth Muscle Cells Expressing AEQ-GFP in Mitochondria are genetically engineered primary or immortalized airway smooth muscle cells designed to express the calcium-sensitive reporter aequorin (AEQ) fused with Green Fluorescent Protein (GFP) specifically targeted to the mitochondria. These cells enable real-time monitoring of mitochondrial calcium signaling, mitochondrial dynamics, and cellular responses in pulmonary research applications.
The GFP tag allows fluorescent visualization of mitochondrial localization, while the AEQ reporter enables sensitive bioluminescent calcium detection.
Key Features
Catalog Number: NBP-0121AEQGFP-Mito
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
These cells maintain characteristic smooth muscle morphology and express key airway smooth muscle markers such as:
-Smooth Muscle Actin (-SMA)
SM22
Calponin
Desmin
Myosin Heavy Chain (SM-MHC)
Quick Facts
Product Type
Engineered Human Airway Smooth Muscle Cells
Viability
High viability
Applications
-Pulmonary Disease Research Asthma studies COPD…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Pulmonary Disease Research Asthma studies COPD research Airway remodeling analysis Pulmonary fibrosis investigations -Mitochondrial Function Studies Mitochondrial calcium signaling Oxidative stress response Mitochondrial membrane potential analysis Bioenergetics and respiration assays -Calcium Signaling Assays GPCR-mediated calcium flux Intracellular calcium dynamics Drug-induced calcium response screening -Drug Discovery & Toxicology Bronchodilator screening Respiratory therapeutic development Mitochondrial toxicity testing Inflammation pathway modulation studies
Suitable for -pulmonary disease research asthma studies copd research airway remodeling analysis pulmonary fibrosis investigations -mitochondrial function studies mitochondrial calcium signaling oxidative stress response mitochondrial membrane potential analysis bioenergetics and respiration assays -calcium signaling assays gpcr-mediated calcium flux intracellular calcium dynamics drug-induced calcium response screening -drug discovery & toxicology bronchodilator screening respiratory therapeutic development mitochondrial toxicity testing inflammation pathway modulation studies studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
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