Human Ovarian Microvascular Endothelial Cells
Quick Actions
Product Overview
Description
Human Ovarian Microvascular Endothelial Cells (HOMECs) are primary endothelial cells isolated from the microvasculature of human ovarian tissue. These cells line the small blood vessels within the ovary and play an essential role in angiogenesis, vascular permeability, hormone transport, and ovarian follicle development. HOMECs are widely used in reproductive biology, ovarian cancer research, inflammation studies, and angiogenesis-related assays.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0015
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Cobblestone-like endothelial morphology
Positive expression of endothelial markers:
CD31 (PECAM-1)
VE-Cadherin
vWF (von Willebrand Factor)
CD144
eNOS
Ability to uptake Ac-LDL
Capable of forming capillary-like tube structures in Matrigel assays
High proliferative potential under optimized endothelial culture conditions
Sensitive to angiogenic growth factors such as VEGF and FGF
Suitable for both normal ovarian physiology and disease modeling
Quick Facts
Product Type
Human Endothelial cells
Viability
>90% viability post-thaw
Applications
1. Angiogenesis Research Evaluation of pro-angio…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
1. Angiogenesis Research Evaluation of pro-angiogenic and anti-angiogenic compounds. Investigation of ovarian vascular remodeling. VEGF signaling studies. 2. Ovarian Cancer Research Tumor angiogenesis modeling. Study of endothelial-tumor interactions. Drug screening for anti-vascular therapies. 3. Reproductive Biology Follicular development studies. Corpus luteum vascularization. Hormonal regulation of ovarian blood vessels. 4. Inflammation Studies Leukocyte-endothelial interactions. Cytokine signaling pathways. Vascular permeability investigations. 5. Drug Discovery and Toxicology Screening of anti-cancer therapeutics. Assessment of vascular toxicity. Evaluation of targeted biologics. 6. Tissue Engineering Development of vascularized ovarian tissue constructs. Regenerative medicine applications. Organ-on-a-chip models.
Suitable for 1. angiogenesis research evaluation of pro-angiogenic and anti-angiogenic compounds. investigation of ovarian vascular remodeling. vegf signaling studies. 2. ovarian cancer research tumor angiogenesis modeling. study of endothelial-tumor interactions. drug screening for anti-vascular therapies. 3. reproductive biology follicular development studies. corpus luteum vascularization. hormonal regulation of ovarian blood vessels. 4. inflammation studies leukocyte-endothelial interactions. cytokine signaling pathways. vascular permeability investigations. 5. drug discovery and toxicology screening of anti-cancer therapeutics. assessment of vascular toxicity. evaluation of targeted biologics. 6. tissue engineering development of vascularized ovarian tissue constructs. regenerative medicine applications. organ-on-a-chip models. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
Contact Support
