Human Primary Diabetic Liver Artery Smooth Muscle Cells
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Product Overview
Description
Human Primary Smooth Muscle Cells derived from the arteries of individuals with diabetes mellitus, specifically focusing on those associated with the liver.
These cells play a crucial role in vascular function and health, particularly in the context of diabetes, where they can exhibit altered behavior due to hyperglycemic conditions. Understanding the characteristics and functions of these smooth muscle cells is essential for exploring potential therapeutic targets and mechanisms underlying diabetic vascular complications.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPDS007
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Characterized by positive expression of smooth muscle cell-specific alpha-actin.
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Glucose Toxicity Studies: Testing how high gluco…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Glucose Toxicity Studies: Testing how high glucose concentrations affect cell function and gene expression. -Insulin Resistance Assays: Investigating why the smooth muscle cells in diabetic patients no longer respond properly to insulin's vasodilatory effects. -Drug Screening: Testing new anti-diabetic drugs to see if they have protective effects on the vasculature of the liver. -Mechanobiology: Studying how the stiffness of the diabetic environment alters cell signaling.
Suitable for -glucose toxicity studies: testing how high glucose concentrations affect cell function and gene expression. -insulin resistance assays: investigating why the smooth muscle cells in diabetic patients no longer respond properly to insulin's vasodilatory effects. -drug screening: testing new anti-diabetic drugs to see if they have protective effects on the vasculature of the liver. -mechanobiology: studying how the stiffness of the diabetic environment alters cell signaling. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
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