Human Primary Diabetic Skeletal Muscle Cells
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Product Overview
Description
Human Primary Skeletal Muscle Cells derived from individuals with diabetes. These specialized cells are significant for studying the effects of diabetes on muscle metabolism, insulin sensitivity, and overall cellular function.
Guarantee expansion for a minimum of 2-5 population doubles.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPDS011
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Characterized by positive expression of smooth muscle cell-specific alpha-actin )
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
Drug Discovery: Screening novel anti-diabetic com…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Drug Discovery: Screening novel anti-diabetic compounds (e.g.
Suitable for drug discovery: screening novel anti-diabetic compounds (e.g. studies and research applications
investigating if a drug can resensitize these cells to insulin independent of the pancreas). Mechanistic Studies: Using siRNA or CRISPR-Cas9 to knock down specific genes (e.g.
Suitable for investigating if a drug can resensitize these cells to insulin independent of the pancreas). mechanistic studies: using sirna or crispr-cas9 to knock down specific genes (e.g. studies and research applications
GLUT4
Suitable for glut4 studies and research applications
PGC-1) to understand their role in the maintenance of the diabetic phenotype. Exercise Mimetics: Studying how electrical pulse stimulation (EPS) or pharmacological agents affect contraction-mediated glucose uptake in a "diabetic" environment. Inflammation: Investigating the role of pro-inflammatory cytokines (IL-6
Suitable for pgc-1) to understand their role in the maintenance of the diabetic phenotype. exercise mimetics: studying how electrical pulse stimulation (eps) or pharmacological agents affect contraction-mediated glucose uptake in a "diabetic" environment. inflammation: investigating the role of pro-inflammatory cytokines (il-6 studies and research applications
TNF-) secreted by diabetic muscle.
Suitable for tnf-) secreted by diabetic muscle. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
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