Human Primary Diabetic Tracheal Smooth Muscle Cells
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Product Overview
Description
Human Primary Diabetic Tracheal Smooth Muscle Cells are specialized cells extracted from the trachea of individuals diagnosed with diabetes. These cells play a crucial role in the respiratory system by regulating airway tone and maintaining proper airflow. Their behavior and function may differ from those derived from non-diabetic individuals, particularly in response to various stimuli related to inflammation and hyperglycemic conditions.
Guarantee expansion for a minimum of 2-5 population doubles.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPDS012
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Characterized by positive expression of smooth muscle cell-specific alpha-actin
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
Diabetic Airway Disease: Studying the link betwee…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Diabetic Airway Disease: Studying the link between diabetes and asthma/COPD. Diabetics often have accelerated lung function decline; these cells help explain the mechanistic basis. Airway Remodeling: Investigating how high glucose environments drive hypertrophy and hyperplasia of the airway smooth muscle (ASM) layer. Pharmacodynamics: Testing the efficacy of bronchodilators (beta-agonists
Suitable for diabetic airway disease: studying the link between diabetes and asthma/copd. diabetics often have accelerated lung function decline; these cells help explain the mechanistic basis. airway remodeling: investigating how high glucose environments drive hypertrophy and hyperplasia of the airway smooth muscle (asm) layer. pharmacodynamics: testing the efficacy of bronchodilators (beta-agonists studies and research applications
anticholinergics) in a diabetic metabolic environment
Suitable for anticholinergics) in a diabetic metabolic environment studies and research applications
as diabetes can alter drug receptor sensitivity. Mechanotransduction: Diabetic cells often exhibit altered stiffness and response to mechanical stress (stretch)
Suitable for as diabetes can alter drug receptor sensitivity. mechanotransduction: diabetic cells often exhibit altered stiffness and response to mechanical stress (stretch) studies and research applications
which is crucial for understanding breathing mechanics in obese/diabetic populations.
Suitable for which is crucial for understanding breathing mechanics in obese/diabetic populations. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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