Human Pulmonary Artery Smooth Muscle Cells Expressing AEQUORIN-GFP in Mitochondria
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Product Overview
Description
Human Pulmonary Artery Smooth Muscle Cells expressing AEQUORIN-GFP in mitochondria are engineered primary-like vascular smooth muscle cells designed for studying mitochondrial calcium signaling, pulmonary vascular biology, smooth muscle contraction, oxidative stress, and pulmonary hypertension mechanisms.
The AEQUORIN-GFP reporter is localized to the mitochondria, allowing visualization of mitochondrial structure through GFP fluorescence and measurement of mitochondrial calcium activity using aequorin-based luminescence assays.
Guarantee expansion for a minimum of 2-5 population doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0101AEQ-GFP-Mito
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characteristics:
Species: Human
Tissue Origin: Pulmonary artery
Cell Type: Vascular smooth muscle cells
Reporter: Mitochondria-targeted AEQUORIN-GFP
Fluorescence: GFP-positive mitochondria
Morphology: Spindle-shaped smooth muscle morphology
Quick Facts
Product Type
Human Smooth Muscle Cells
Viability
>90% viability post-thaw
Applications
-Mitochondrial calcium signaling studies -Pulmon…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Mitochondrial calcium signaling studies -Pulmonary hypertension research -Vascular smooth muscle contraction studies -Drug screening for pulmonary vascular disease -Mitochondrial toxicity assays -Oxidative stress and hypoxia-response studies -Live-cell imaging of mitochondrial dynamics -Calcium flux assays using aequorin luminescence
Suitable for -mitochondrial calcium signaling studies -pulmonary hypertension research -vascular smooth muscle contraction studies -drug screening for pulmonary vascular disease -mitochondrial toxicity assays -oxidative stress and hypoxia-response studies -live-cell imaging of mitochondrial dynamics -calcium flux assays using aequorin luminescence studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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