Human Lung Airway Smooth Muscle Cells Expressing AEQGFP in Cytoplasm
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Product Overview
Description
Human Lung Airway Smooth Muscle Cells (HLASMCs) Expressing AEQ-GFP in Cytoplasm are genetically engineered primary airway smooth muscle cells designed for advanced calcium signaling and live-cell imaging studies. These cells express a fusion of Aequorin (AEQ) and Green Fluorescent Protein (GFP) localized within the cytoplasm, enabling real-time monitoring of intracellular calcium flux and cellular dynamics.
These cells maintain the characteristic morphology and functional properties of native airway smooth muscle cells while providing enhanced fluorescent visualization and bioluminescent calcium detection capabilities.
Key Features
Catalog Number: NBP-0121AEQGFP-cyto
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Positive expression markers:
-Myosin Heavy Chain (SM-MHC)
-GFP fluorescence for live-cell tracking and imaging
-Responsive to bronchoconstrictive agonists and calcium stimulation
-Suitable for fluorescence microscopy and calcium imaging assays
-Adherent growth pattern
-High transfection compatibility for respiratory research applications
Quick Facts
Product Type
Human Endothelial cells
Viability
High viability
Applications
-Airway remodeling studies -Asthma and COPD rese…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Airway remodeling studies -Asthma and COPD research -Intracellular calcium signaling assays -GPCR signaling analysis -Drug screening for bronchodilators and anti-inflammatory compounds -Live-cell fluorescence imaging -Cytoplasmic protein trafficking studies -Respiratory disease modeling -Toxicology and pulmonary pharmacology research -High-content imaging platforms
Suitable for -airway remodeling studies -asthma and copd research -intracellular calcium signaling assays -gpcr signaling analysis -drug screening for bronchodilators and anti-inflammatory compounds -live-cell fluorescence imaging -cytoplasmic protein trafficking studies -respiratory disease modeling -toxicology and pulmonary pharmacology research -high-content imaging platforms studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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