Human Liver Lymphatic Endothelial Cells
Quick Actions
Product Overview
Description
Human Liver Lymphatic Endothelial Cells (HLLECs) are specialized endothelial cells that line the lymphatic vessels within the liver. These cells play a crucial role in maintaining fluid homeostasis, immune cell trafficking, lipid transport, and liver immune surveillance. HLLECs contribute significantly to liver physiology and are increasingly recognized for their involvement in chronic liver diseases, fibrosis, inflammation, and cancer metastasis.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0038
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
CELL CHARACTERISTICS
-Morphology:
Typical cobblestone-like endothelial morphology when cultured in vitro.
Form interconnected monolayers with strong cell-cell junctions.
Exhibit elongated cellular structures during lymphangiogenic activation.
-Phenotypic Markers
Human Liver Lymphatic Endothelial Cells commonly express:
-LYVE-1
-Podoplanin (PDPN)
-PROX1
-VEGFR-3
-CCL21
-Functional Properties
Regulate lymphatic fluid drainage from liver tissue.
Facilitate immune cell migration and antigen transport.
Participate in inflammatory and fibrotic responses.
Respond to lymphangiogenic growth factors such as VEGF-C and VEGF-D.
Contribute to liver regeneration and tissue remodeling.
Quick Facts
Product Type
Human Endothelial cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
-Liver Disease Research Investigation of liver f…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Liver Disease Research Investigation of liver fibrosis and cirrhosis. Studies of chronic hepatitis and inflammatory liver disorders. Analysis of lymphatic remodeling during liver injury. -Cancer Research Tumor lymphangiogenesis studies. Investigation of metastatic pathways in liver cancers. Evaluation of anti-lymphangiogenic therapeutic strategies. -Immunology Research on hepatic immune surveillance. Leukocyte trafficking and antigen presentation studies. Liver transplant immunology investigations.
Suitable for -liver disease research investigation of liver fibrosis and cirrhosis. studies of chronic hepatitis and inflammatory liver disorders. analysis of lymphatic remodeling during liver injury. -cancer research tumor lymphangiogenesis studies. investigation of metastatic pathways in liver cancers. evaluation of anti-lymphangiogenic therapeutic strategies. -immunology research on hepatic immune surveillance. leukocyte trafficking and antigen presentation studies. liver transplant immunology investigations. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
Contact Support
