Human Primary Diabetic Skeletal Muscle Cells
Quick Actions
Product Overview
Description
Human Primary Diabetic Skeletal Muscle Cells are cryopreserved primary skeletal-muscle cells for in vitro research. The product supports tissue-relevant mechanistic studies, disease modeling, assay development, pharmacology, and cell-biology applications. Early-passage use and standardized culture conditions are recommended to minimize phenotype drift.
Guarantee expansion for a minimum of 2-5 population doubles.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBPDS011
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
Characterization Markers
Characterized by positive expression of smooth muscle cell-specific alpha-actin )
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Applications
Drug Discovery: Screening novel anti-diabetic com…
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
Drug Discovery: Screening novel anti-diabetic compounds (e.g.
Suitable for drug discovery: screening novel anti-diabetic compounds (e.g. studies and research applications
investigating if a drug can resensitize these cells to insulin independent of the pancreas). Mechanistic Studies: Using siRNA or CRISPR-Cas9 to knock down specific genes (e.g.
Suitable for investigating if a drug can resensitize these cells to insulin independent of the pancreas). mechanistic studies: using sirna or crispr-cas9 to knock down specific genes (e.g. studies and research applications
GLUT4
Suitable for glut4 studies and research applications
PGC-1) to understand their role in the maintenance of the diabetic phenotype. Exercise Mimetics: Studying how electrical pulse stimulation (EPS) or pharmacological agents affect contraction-mediated glucose uptake in a "diabetic" environment. Inflammation: Investigating the role of pro-inflammatory cytokines (IL-6
Suitable for pgc-1) to understand their role in the maintenance of the diabetic phenotype. exercise mimetics: studying how electrical pulse stimulation (eps) or pharmacological agents affect contraction-mediated glucose uptake in a "diabetic" environment. inflammation: investigating the role of pro-inflammatory cytokines (il-6 studies and research applications
TNF-) secreted by diabetic muscle.
Suitable for tnf-) secreted by diabetic muscle. studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
Technical Support
Our experts are available for technical questions and protocol assistance.
Contact Support
