Human VEGFR2 shRNA Stable Transfected RFP-HUVECs
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Product Overview
Description
These specialized cells offer a highly effective in vitro model for investigating the intricacies of endothelial biology, with a particular focus on the processes of angiogenesis, the mechanisms of vascular signaling, and the implications of gene knockdown.
By silencing the VEGFR2 gene and incorporating red fluorescent protein (RFP) labeling, researchers can conduct detailed functional analyses and perform live-cell imaging, enabling them to visualize and study cellular behaviors and interactions in real time.
Guarantee expansion for a minimum of 2-5 population
doublings.
IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features
Catalog Number: NBP-0001-siRNAVR2RFP
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)
-Genetic Modification: Stable integration of shRNA targeting VEGFR2 (VEGFR2 (KDR))
-Fluorescent Marker: Constitutive RFP expression for real-time visualization
-Cell Type: Primary-derived endothelial cells from human umbilical vein (HUVECs)
-Stable Knockdown: Long-term suppression of VEGFR2 signaling
-Morphology: Typical cobblestone endothelial monolayer under standard culture conditions
-High Utility: Suitable for imaging, functional assays, and signaling studies
Quick Facts
Product Type
Human Endothelial cells
Viability
>85% viable (Post-thaw)
Applications
-Angiogenesis research -Cancer microenvironment …
Availability
In Stock • Global Shipping
Technical Specifications
Primary Applications
Applications & Use Cases
Primary Applications
-Angiogenesis research -Cancer microenvironment and tumor vascularization studies -Drug screening targeting VEGF/VEGFR signaling -Gene silencing and RNAi mechanism studies -Live-cell fluorescence imaging of endothelial dynamics -Vascular permeability and migration assays
Suitable for -angiogenesis research -cancer microenvironment and tumor vascularization studies -drug screening targeting vegf/vegfr signaling -gene silencing and rnai mechanism studies -live-cell fluorescence imaging of endothelial dynamics -vascular permeability and migration assays studies and research applications
Research Areas
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Disease Modeling
Pathophysiology research
Support & Resources
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